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    #31
    R.i.p. Garfield 1986-2016 Garfield's Avatar
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    youre right nothing turns on a fat mexican from tennessee like telling her how uch you know about vicodin
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    #32
    I am postulate one blumpkin blownuts's Avatar
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    Quote Originally Posted by Plug Drugs View Post
    not when you snort it... bioavailability of insufflated morphine is something like 10x higher than oral BA
    where are you getting your info from
    morphine sulphate has the lowest BA when snorted compared to other roa's

    other salts of morphine do have good nasal BA, particularly HCl
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    #33
    Pariah :Care:y Plug Drugs's Avatar
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    although i can agree that hydrocodone has its own sort of special euphoria about it that oxy can't provide (no matter what the dose), oxy is still a far more potent opioid (i'd say its got to be at least twice as potent in terms of analgesia).
    Plus, who the hell wants to do a cold water extraction on vicodin to take their bi-daily 100mg dose and lose 10% of the hydro in the process, when there is perfectly good 30mg roxicodone available that can be readily eaten in the form its in
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    #34
    Pariah :Care:y Plug Drugs's Avatar
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    and lets not forget how short hydro's duration is compared to oxy -- some times i've been high off oxy a full 12 hours after taking my dose. Hydro rarely has any effect after 5 hours.
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    #35
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    Quote Originally Posted by blumpkin blownuts View Post
    where are you getting your info from
    morphine sulphate has the lowest BA when snorted compared to other roa's

    other salts of morphine do have good nasal BA, particularly HCl
    wasn't looking into the whole salt business.
    Couldn't a simple procedure involving simply household items be performed to remove the base? Or i bet morphine sulfate could at least be plugged (salts can't affect the BA of anal administration)
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    #36
    R.i.p. Garfield 1986-2016 Garfield's Avatar
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    vicodin is to crack what morphine is to coke
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    #37
    R.i.p. Garfield 1986-2016 Garfield's Avatar
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    i just wanna stick grapes up my ass to absorb the vitamin c
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    #38
    I am postulate one blumpkin blownuts's Avatar
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    hc is a pro-drug... it has to be oxidized into hm by CYP450 3A4 to have any psychoactive effect
    which means if you want it to work, you can't potentiate it by taking CYP450 inhibitors

    oc is psychoactive before oxidation. it oxidizes to om, which has a short peak plasma half-life. an oc high generally doesn't last longer than 5-6hr without coadminning a CYP450 inhibitor
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    #39
    R.i.p. Garfield 1986-2016 Garfield's Avatar
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    yeah right like bob actually memorized all thhose random numbers
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    #40
    I am postulate one blumpkin blownuts's Avatar
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    Quote Originally Posted by Plug Drugs View Post
    wasn't looking into the whole salt business.
    Couldn't a simple procedure involving simply household items be performed to remove the base? Or i bet morphine sulfate could at least be plugged (salts can't affect the BA of anal administration)
    yes the sulphate has best BA when plugged (obviously barring IV)
    and you can get morphine hcl from morphine so4 by adding muriatic acid, then carefully adding lye until pH-neutral
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    #41
    Pariah :Care:y Plug Drugs's Avatar
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    i hope you get a readily available cheap connection to 30mg instant release oxycodone and you can tell us about how your tolerance shot up to 400mg a day and you sold everything you owned to avoid withdrawals and started plugging it up your ass instead of eating it if you had just eaten a meal (because you dont want the contents of your stomach to wreck the bioavailability). So then you check into a methadone clinic and wait in line with the biggest scum in town every day and you'll never even be able to dream of feeling vicodin again no matter how many you take

    then tell me about how good your shitty vicodin is
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    #42
    I am postulate one blumpkin blownuts's Avatar
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    Quote Originally Posted by Garfield View Post
    yeah right like bob actually memorized all thhose random numbers
    i abused opiates for 14 yrs...
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    #43
    Pariah :Care:y Plug Drugs's Avatar
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    that was directed at garfield btw
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    #44
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    Quote Originally Posted by Garfield View Post
    yeah right like bob actually memorized all thhose random numbers
    he's 100% right, and those aren't "numbers" they are enzymes you twit
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    #45
    R.i.p. Garfield 1986-2016 Garfield's Avatar
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    wow yall seriously cant handle your shit. sorry for partying
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    #46
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    Quote Originally Posted by blumpkin blownuts View Post

    oc is psychoactive before oxidation. it oxidizes to om, which has a short peak plasma half-life. an oc high generally doesn't last longer than 5-6hr without coadminning a CYP450 inhibitor
    i can personally testify that oxy highs can last 8-12 hours when i just start a binge and narrow down to about 4-5 hours at the end of my binge
    be reminded that the pharmacokinetics of any opiate aren't 100% the same between individuals
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    #47
    Pariah :Care:y Plug Drugs's Avatar
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    Quote Originally Posted by Garfield View Post
    wow yall seriously cant handle your shit. sorry for partying
    i can handle myself perfectly fine; i still manage to pay the bills and rent while maintaining my opiate use..
    I just don't think that you are the kind of person who could handle himself when a real opiate connection comes along
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    #48
    R.i.p. Garfield 1986-2016 Garfield's Avatar
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    man i guessim just not as cool as you are
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    #49
    I am postulate one blumpkin blownuts's Avatar
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    Quote Originally Posted by Plug Drugs View Post
    be reminded that the pharmacokinetics of any opiate aren't 100% the same between individuals
    that's very true
    the liver enzymes in particular can vary alot from genetics, diet, usage patterns etc
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    #50
    I am postulate one blumpkin blownuts's Avatar
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    Quote Originally Posted by Plug Drugs View Post
    i can handle myself perfectly fine; i still manage to pay the bills and rent while maintaining my opiate use..
    I just don't think that you are the kind of person who could handle himself when a real opiate connection comes along
    i lost control once i had legit medical need and was forced to take it every day, then several times a day..
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    #51
    Pariah :Care:y Plug Drugs's Avatar
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    you were trying to tell us (in what i think was seriousness) that hydrocodone is better than morphine or oxy, which just isn't true.
    I'll admit, there is a sort of euphoria that is unique to hydrocodone/hydromorphone that oxy can't achieve, but a daily user is never going to pick hydrocodone over morphine or oxy -- and youll know exactly what i'm talking about as soon as someone comes to you with a cheap oxy connection
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    #52
    R.i.p. Garfield 1986-2016 Garfield's Avatar
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    bobs unergonomic keybpard ruined his life
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    #53
    I am postulate one blumpkin blownuts's Avatar
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    if it was opiates alone i might have been able to manage, but taking it every day with alcohol pot benzos barbs soma phenergan and dxm got to be unmanageable from a mental/emotional health standpoint
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    #54
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    Quote Originally Posted by Garfield View Post
    bobs unergonomic keybpard ruined his life
    i blew a bunch of discs in my back, ask your mom how
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    #55
    R.i.p. Garfield 1986-2016 Garfield's Avatar
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    dxm?? lol why the fuck would you mix all of those with walgreen nyquil
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    #56
    R.i.p. Garfield 1986-2016 Garfield's Avatar
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    Quote Originally Posted by blumpkin blownuts View Post
    i blew a bunch of discs in my back, ask your mom how
    what else did you blow?
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    #57
    I am postulate one blumpkin blownuts's Avatar
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    Quote Originally Posted by Garfield View Post
    dxm?? lol why the fuck would you mix all of those with walgreen nyquil


    i bet plug knows
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    #58
    Pariah :Care:y Plug Drugs's Avatar
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    one time i tried taking 50mg of hydrocodone the day after a 3 day 30mg twice a day oxy binge, and didn't feel a damn thing. In terms of analgesia, hydrocodone is sort of a joke
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    #59
    I am postulate one blumpkin blownuts's Avatar
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    and i had pure dxm powder, thought i was pretty smart until i had a toxic reflex from all the accumulated bromide
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    #60
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    dxm lowers opiate tolerance, and can potentiate analgesia. DXM is an NMDA antagonist just like PCP or Ketamine; its just far more readily available and more easily attainable than PCP or ketamine
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